| 1999 Selected Abstracts from American Urological Association annual meeting |
Neural Stimulation as a method of controlling prostatitis symptoms
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Submitter's note: |
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September 10, 1999 |
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Neural Stimulation is a therapy which can be effective for patients with
pain and voiding dysfunction, particularly if anti-microbial or
anti-inflammatory based therapies are unsuccessful. I have no personal
experience with the technique, which is quite technically involved, but
here is a synopsis provided to me by Dr. Stuart Chalfin, a urologist in
our community with considerable experience. I have started to refer
patients to him, but it is too early to tell how effective this might be
for CPPS patients. If anyone is interested in more information, his
office number for appointments is (562) 598-6166. |
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Please don't email me for more info on this technique or for a list of
people in your area who perform it: what I have posted here is all I
know.
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Submitted by:
Daniel Shoskes MD
UCLA
http://www.ben2.ucla.edu/~dshoskes
Institute for Male Urology
http://www.urol.com
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Sacral Nerve Root Stimulation |
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Over one million people in the United States alone have problems
with frequent voiding and unstable bladder disease. A recent study in
Germany estimated that ten per cent of the adult female population
suffered from this disorder. Bladder retraining, pelvic floor
exercises, biofeedback, and anti-cholinergic drug therapy
(oxybutynin,tolterodine) are effective measures to treat this problem.
However, some patients remain resistant to therapy. For this group of
patients, unilateral sacral nerve stimulation offers a safe and
nondestructive alternative. It has rapidly replaced major and often
unsuccessful surgery as the primary form of therapy in this difficult
group of patients. It's usage for chronic prostatitis and interstitial
cystitis is growing. |
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The therapy works by applying chronic electrical stimulation to
sensory nerves that supply the bladder, rectum and pelvic floor.
Overactive reflexes that drive the frequency and incontinence are "shut
off" by this therapy. The bladder once again can remain quiet until
the appropriate time to void is reached. The therapy also works for
some syndromes of urinary retention. These patients are unable to void
and are forced to pass catheters through their urethra in order to
void. This less common condition is also known as "Fowlers Syndrome". |
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Candidates for the therapy can first be tested in the office with a
technique called per-cutaneous nerve evaluation. (P.N.E.) Utilizing a
local anesthetic, the doctor can place a wire electrode through the
skin and holes or foramen in the sacrum. (The area just above the
crease of the buttocks) This leaves the electrode in an area where it
is in close contact with the nerves that run in and out of the bladder
and pelvis. The technique is very safe and there have not been any long
term complications associated with it. After a special dressing and
tape are applied, the wire is connected to a stimulator box. The
patient can then go home and function normally with the device for a
period of three days to two weeks. At the end of the test period,
both the patient and doctor can determine if the therapy is successful.
Thus the patient can take a safe "test drive" with the device prior to
any permanent implantation. There are very few treatments in medicine
that offer this advantage.
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Patients who are candidates for a permanent implant are admitted
overnight after a small surgery. The surgery is performed through two
incisions on the buttocks. A wire electrode and a small generator
similar to a pacemaker are implanted. The device is activated via a
computer and radio transmitter within 48 hours in the doctor's office.
The patient can then control the device with a hand held transmitter
that looks and functions very similar to a television remote control. |
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Long term success has been excellent. In a multi-center,
randomized prospective clinical trial for this therapy, at six-month
follow-up, 75% of implanted patients had a reduction in frequency of
leaking episodes of 50% or greater and 47% of the implanted patients
were dry. At 12-month follow-up, 79% of implanted patients had a
reduction in frequency of leaking episodes of 50% or greater and 45% of
the implanted patients were dry. This treatment is approved for
patients with frequent voiding and results have also been excellent in
this group of patients. Currently, sufferers of interstitial
cystitis, chronic prostatitis and other pelvic pain syndromes are
undergoing clinical trials to determine the success of neurostimulation
this group of patients. |
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Neurostimulation is an exciting, newly approved therapy for chronic
voiding problems in both men and women. Now and in the future, it
will increasingly be utilized to treat patients with these disorders.
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Stuart A. Chalfin, M.D.
Associates in Urology
Los Alamitos, California
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